Optical Genome Mapping Market Size, Share, Industry, Forecast and Outlook (2024-2031)

Global Optical Genome Mapping Market By Product Type (Consumables, Instruments, Software) By Application (Structural Variant Detection, Genome Assembly, Microbial Strain Typing, Others) By End User (Biotechnology and Pharmaceutical Companies, Clinical Laboratories, Academic research institutes, Others) and By Region (North America, Europe, South America, Asia Pacific, Middle East, and Africa) – Share, Size, Outlook, and Opportunity Analysis, 2024-2031

Market Overview

Global Optical Genome Mapping Market reached US$ YY million in 2023 and is expected to reach US$ YY million by 2031, growing with a CAGR of YY% during the forecast period 2024-2031.

Optical Genome Mapping (OGM) is an imaging technology which evaluates the fluorescent labelling pattern of individual DNA molecules to perform an unbiased assessment of genome-wide structural variants down to 500 base pairs (bp) in size,6 a resolution that far exceeds conventional cytogenetic approaches.

Optical Genome Mapping relies on a specifically designed extraction protocol facilitating the isolation of ultra-high molecular weight (UHMW) DNA. This protocol utilizes a paramagnetic disk purposed with trapping DNA for wash steps thereby reducing sheering forces present in standard column-based extraction methods. The result is DNA fragments of ~150 kilobases (kb) to megabases (Mbp) in size, ~5-10x longer than the average fragment size from conventional DNA isolation techniques. 

Market Scope

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Market Dynamics: Drivers and Restraints

Increasing advancements in optical mapping technologies

Continuous advances in optical mapping technology have been significant in market expansion. High-resolution imaging, DNA labelling, and data processing algorithms have increased the accuracy and efficiency of optical genome mapping, making it a viable option for a variety of applications such as genome assembly, structural variation identification, and genotyping.

For instance, in January 2023, Bionano Genomics announced the launch of several new products and advancements for its optical genome mapping workflow, including improved sample preparation robustness, faster turnaround time for DNA labelling and imaging, and increased throughput and quality metrics. Bionano's new sample prep kits, chips, and instrument software respond to customer feedback and can increase performance in a greater volume of routine genome analysis applications.

Furthermore, the global optical genome mapping market is also driven by various other factors like Rising government funding and research initiatives, Advancements in genomic research and others which help the market to grow during the forecast period. 

Market Dynamics: Restraint

Ethical privacy concerns, the precise genetic data offered by optical genome mapping raises ethical considerations about patient privacy and consent. Protecting sensitive genetic data and ensuring that patients fully understand the ramifications of genomic testing are key difficulties that must be solved in order to increase public trust and confidence in the technology.

Furthermore, Regulatory hurdles, integration with existing systems and other factors also hamper the market growth during the forecast period. 

Segment Analysis

The global optical genome mapping market is segmented based on product type, application, end-user and region.

The consumables segment from the product type segment accounted for approximately 43.5% of the  optical genome mapping market share

The consumables segment from the product type segment accounted for approximately 43.5% and is expected to dominate during the forecast period. Consumables in the optical genome mapping market comprise a variety of essential items. Microfluidic chips, optical chips, and other specialized materials form the backbone of the technology. These consumables are meticulously designed to facilitate the precise handling and analysis of genetic samples. Researchers and technicians rely on these consumables to ensure the integrity of the genetic material throughout the mapping process.

For instance, in February 2022, Arima Genomics launched two new product offerings named Arima-HiC+ FFPE kit in which scientists will be able to find and discover structural variants in their 3D genomic data with this tool. By combining structural variant detection with 3D genome orientation data, researchers will gain a better understanding of how variants affect gene and cellular function. Finally, these findings will benefit scientists in the discovery of novel disease mechanisms and therapeutic targets.

Geographical Analysis

North America accounted for approximately 38.4% of the market share in 2022

North America is estimated to hold about 38.4% of the total market share throughout the forecast period, owing to the factors like a rise in genomics research and biotechnology advancements, collaborations and acquisitions. Also including a strong presence of leading biotechnology and pharmaceutical companies, extensive government funding for genomics research, and a robust healthcare infrastructure helps the region hold the highest market share during the forecast period.

For instance, in October 2021, Bionano Genomics announced the acquisition of BioDiscovery, a leading software company with high-class solutions for the analysis, interpretation, and reporting of genomics data. The Bionano and BioDiscovery teams will collaborate to create a version of NxClinical that includes optical genome mapping data alongside existing next-generation sequencing and microarray data types. Future goals include RNA expression profiling, epigenetics including methylation, and maybe proteomics in the future.

COVID-19 Impact Analysis

The COVID-19 pandemic aided the optical genome mapping market. During the early phases of the pandemic, labs and research institutes throughout the world had to redirect their resources and focus on COVID-19 diagnoses, treatment, and vaccine development. This caused a brief halt in non-COVID-related scientific endeavours, such as genomics. 

Competitive Landscape

The major global players in the market include Bionano Genomics, Nucleome Informatics Private Limited, Praxis Genomics, LLC, MedGenome, INRAE (French Plant Genomic Resources Center (CNRGV)), PerkinElmer (PerkinElmer Genomics), Genohub Inc, Hofkens Lab, Cerba, Nabsys and among others.

Key Developments

• In August 2023, Bionano Genomics, Inc. stated its participation at the Cancer Genomics Consortium (CGC) 2023 Annual Meeting with a broad range of content covering the utility of optical genome mapping (OGM) for solid tumour and haematological malignancy cancer research, including scientific platform and poster presentations from Bionano and a panel discussion featuring esteemed researchers from across the cancer genomics landscape.
• In July 2023, the Centre for Cellular and Molecular Biology (CCMB) launched a state-of-the-art very high-end next-generation genetic testing method ‘Optical Genome Mapping’ (OGM) with the ability to accurately detect genomic abnormalities that cause various kinds of genetic ailments in humans.
• In March 2023, Bionano Genomics launched two novel OGM-based clinical tests, OGM-Dx prenatal whole genome structural variant and OGM-Dx postnatal whole genome structural variant.

Why Purchase the Report?

• To visualize the global optical genome mapping market segmentation based on product type, application, end user and region as well as understand key commercial assets and players.
• Identify commercial opportunities by analysing trends and co-development. 
• Excel data sheet with numerous data points of optical genome mapping market-level with all segments.
• PDF report consists of a comprehensive analysis after exhaustive qualitative interviews and an in-depth study.
• Product mapping available as excel consisting of key products of all the major players.

The global optical genome mapping market report would provide approximately 77 tables, 79 figures and 187 Pages.

Target Audience 2024

• Manufacturers/ Buyers
• Industry Investors/Investment Bankers
• Research Professionals
• Emerging Companies