Cell Expansion Market Size, Share, Industry, Forecast and outlook (2024-2031)

Report Overview

Global Cell Expansion Market reached US$ 20 billion in 2023 and is expected to reach US$ 55 billion by 2031, growing at a CAGR of 15.3% during the forecast period 2024-2031.

Cell expansion is the process of culturing isolated cells for multiple generations to achieve the desired number of cells for a regenerative response in a patient. This involves serial passages in closed culture vessels and the use of culture medium to remove metabolites and provide nutrients. 

Moreover, cell expansion is a crucial process in Biotechnology and regenerative medicine, aiming to increase the quantity of specific cell types for therapeutic applications. It is essential for developing cell-based therapies, such as stem cells and immune cells, which require large numbers of cells. Cell expansion's significance lies in producing functional cells for cancer immunotherapy, tissue engineering, and regenerative medicine.

Market Scope

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Market Dynamics: Drivers & Restraints

Rise in the prevalence of chronic diseases

The global cell expansion market is expanding due to the rise in chronic diseases like cancer, diabetes, and autoimmune disorders. This has led to a demand for advanced therapies like regenerative medicine, cell-based therapies, and personalized treatments. Cell expansion is crucial for developing these treatments, and healthcare providers and researchers are seeking innovative solutions to meet the global need for effective treatment options.

For instance, in 2023, according to Institute for Health Metrics and Evaluation, Diabetes affects over half a billion people globally, affecting men, women, and children of all ages. The number is projected to double to 1.3 billion in the next 30 years, with every country experiencing an increase. The global prevalence rate is 6.1%, making diabetes one of the top 10 leading causes of death and disability. North Africa and the Middle East have the highest rate at 9.3%, which is projected to rise to 16.8% by 2050.

Ethical concern related to cell biology

Ethical concerns in cell biology are limiting the cell expansion market. The use of embryonic stem cells, which involve human embryo destruction, has led to restrictions in many countries. Adult stem cells, an ethical alternative, often involve invasive procedures, raising concerns about patient consent and safety. Genetically modified cells pose potential risks to patients and the environment. These ethical concerns are hindering the growth of the cell expansion market. 

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Market Segment Analysis

The global cell expansion market is segmented based on product type, cell type, application, end user and region.

The instruments from the product type segment accounted for approximately 41.3% of the cell expansion  market share

The instruments from the product type segment accounted for approximately 41.3%. Instruments are crucial in cell expansion, enabling controlled growth and multiplication for therapeutic and research purposes. Automated bioreactors, cell counters, centrifuges, and incubators maintain optimal conditions during cell culture, ensuring consistency, scalability, and efficiency. These devices are essential for regenerative medicine, immunotherapy, and tissue engineering. Advanced instrumentation improves cell viability and yield reduces contamination risks, and produces high-quality cells for clinical use.

For instance, in September 2024, 10x Genomics, Inc. launched Chromium Xo, a new single cell instrument designed for researchers seeking high-quality data on limited budgets. This affordable entry point into routine, high-performance single cell analysis is part of its fleet of Chromium single cell instruments.

Market Geographical Share

North America is estimated to hold about 38.4% of the total market share throughout the forecast period

North America is estimated to hold about 38.4% of the total market share throughout the forecast period due to rising cancer incidence, increased government funding, research on stem cell therapies, and increased awareness of advanced treatment methods. 

For instance, in October 2024, Aspen Neuroscience, Inc., a private biotechnology company developing personalized (autologous) cell therapies, announced the expansion of its San Diego footprint near its headquarters in Torrey Pines, with a new 22,000 square foot facility for GMP manufacturing of induced pluripotent stem cell (iPSC)-derived cell therapies.

Moreover, in August 2024, Pluri Inc has been granted a US patent for a new method for expanding immune cells using proprietary 3D cell expansion technology. This technology mimics the natural lymph node-like environment of immune cells within the human body, providing cells with the necessary conditions for efficient expansion at scale and quality.

Market Segmentation

By Product Type

• Automated Cell Expansion Systems
• Instruments
  • Cell Expansion Supporting Equipment
  • Cell Counters
  • Flow Cytometers
  • Centrifuges
  • Other Supporting Equipment
  • Others
• Consumables
  • Reagents
  • Media
  • Disposables
  • Tissue Culture Flasks
  • Others
• Bioreactors
  • Microcarrier Bioreactors
  • Microcarrier-based anchorage-dependent bioreactors
  • Suspension-based anchorage-independent bioreactors
  • Perfusion/Hollow Fibre Bioreactors

By Cell Type

• Animal Cells
• Human Cells
• Stem Cells (SCs)
• Adult Stem Cells
• Others

By Application

• Regenerative Medicine and Stem Cell Research
• Clinical Studies
• Vaccine Production
• Others

By End User

• Biopharmaceutical & Biotechnology Companies
• Research Institutes
• Hospitals
• Diagnostic Laboratories
• Others 

By Region

• North America
  • U.S.
  • Canada
  • Mexico
• Europe
  • Germany
  • UK
  • France
  • Italy
  • Spain
  • Rest of Europe
• South America
  • Brazil
  • Argentina
  • Rest of South America
• Asia-Pacific
  • China
  • India
  • Japan
  • South Korea
  • Rest of Asia-Pacific
• Middle East and Africa

Competitive Landscape

The major global players in the market include Thermo Fisher Scientific, Inc, Merck KGaA, Becton, Dickinson and Company, GE Healthcare, Terumo BCT, Beckman Coulter Inc, Miltenyi Biotec, Stemcell Technologies, Inc., Takara Bio Inc., Lnza Group LTD among others.

Key Developments

• In August 2024, HC Corporation Biomedical Division showcased a prototype of its new cell expansion system, LiCellGrow, at the ISCT Europe 2024 Regional Meeting in Gothenburg, Sweden. LiCellGrow allows pharmaceutical companies to visualize real-time metabolic changes in cells and automatically adjust cell culture conditions for optimal growth. It aims to increase the availability of cell and gene therapy products by accelerating the manufacturing of specific cells needed for these therapies.
• In March 2024, Getinge has partnered with the bioprocessing company CellRev in the development of a continuous cell processing platform called Livit ACE (Adherent Cell Expansion). The solution is a breakthrough within allogenic cell therapy manufacturing.

Why Purchase the Report?

• To visualize the global cell expansion market segmentation based on product type, cell type, application, end user and region as well as understand key commercial assets and players.
• Identify commercial opportunities by analyzing trends and co-development.
• Excel data sheet with numerous data points of the cell expansion market level with all segments.
• PDF report consists of a comprehensive analysis after exhaustive qualitative interviews and an in-depth study.
• Product mapping available as excel consisting of key products of all the major players.

The global cell expansion market report would provide approximately 64 tables, 61 figures and 186 pages.

Target Audience 2024

• Manufacturers/ Buyers
• Industry Investors/Investment Bankers
• Research Professionals
• Emerging Companies