Global Vitamin B6 (Pyridoxine) Market is segmented By Drug Type (Tablets, Capsules), By Use (Menopausal depressions, ANAEMIA), By Region (North America, Europe, South America, Asia Pacific, Middle East, and Africa) – Share, Size, Outlook, and Opportunity Analysis, 2022-2029
Vitamin B6 (Pyridoxine) Market Overview
The Global Vitamin B6 (Pyridoxine) Market is expected to reach a CAGR during the forecast period (2022-2029).
For prevention and treatment of low levels of pyridoxine (pyridoxine deficiency) and the anemia vitamin B6 is used. It is also used for depression, premenstrual syndrome (PMS), heart disease and many other conditions.
Vitamin B6 (Pyridoxine) Market Dynamics
Increasing the adoption of vitamin B6 enriched supplements due to their health benefits will drive the market. Demand for vitamin-enriched food and beverages is increasing and will drive the Vitamin B6 (Pyridoxine) Market
Increasing adoption of vitamin B6 enriched supplements due to their health benefits will drive the market
Vitamin B6 is naturally present in many foods, is a water-soluble vitamin and available as a dietary supplement. This vitamin in coenzyme performs a wide variety of functions in the body and is extremely versatile, involving more than 100 enzyme reactions, mostly concerned with protein metabolism. Both PMP and PLP are involved in amino acid metabolism, and PLP is also involved in the metabolism of one-carbon units, lipids and carbohydrates. It also plays a role in cognitive development through the biosynthesis of neurotransmitters and maintains normal levels of homocysteine, an amino acid in the blood. Vitamin B6 is involved in glycogenolysis and gluconeogenesis, immune function (for example, it promotes lymphocyte and interleukin-2 production), and hemoglobin formation.
Vitamin B6 has been widely known for its role in prevention of disease. This in supplement form is most promising for the treatment of pregnancy-induced nausea, but such use should be occurred under the supervision of a physician. Adequate blood levels of B6 may be associated with a lower risk of cancers than low blood levels. However, the use of separate B6 supplements (apart from the RDA amounts in typical multivitamin preparations) is inconclusive and not recommended.
Demand for vitamin-enriched food and beverages is increasing and will drive the vitamin B6 (Pyridoxine) market
Worldwide, more than 2 billion people have micronutrient deficiencies because of insufficient essential minerals and vitamins each day. Food fortification through adding essential minerals and vitamins has been noted to be one of the most cost-effective, fastest and efficient methods used to increase the nutritional value of food products. Consumer awareness of the risk and prevalence of nutrient deficiencies (especially in iron, folic acid, vitamin A, iodine, and zinc) continues to grow, along with the understanding that these deficiencies can be easily corrected through supplementation.
Vitamin B6 is a co-factor in the formation of δ-aminolevulinic acid, a rate-limiting step in heme biosynthesis. Vitamin B6 also plays a potentially important role in the incorporation of iron into protoporphyrin, the final step in heme synthesis. Hence, vitamin B6 is an important nutrient for erythropoiesis.
Stringent rules and regulations imposed on Pyridoxine will hamper the vitamin B6 (Pyridoxine) market
Only two drugs which are approved by FDA containing pyridoxine or its analogs are present. The first is a combination of many vitamins, including B6, indicated for the prevention of vitamin deficiency in adult and pediatric patients receiving parenteral nutrition and the other one is a combination of pyridoxine hydrochloride (a vitamin B6 analog) and doxylamine succinate for treatment of nausea and vomiting of pregnancy in oral tablet form that does not respond to conservative management.
Research shows conflicting results regarding the use of vitamin B6 supplements in treating premenstrual syndrome, gestational diabetes, carpal tunnel syndrome, morning sickness and treating and preventing essential hypertension. Even though scant evidence regarding pyridoxine’s efficacy exists regarding these uses, it has been used empirically to treat some conditions, including atopic dermatitis, dental caries, acute alcohol intoxication, autism, diabetic complications, Down syndrome, schizophrenia, Huntington chorea and steroid-dependent asthma. The only two contraindications for vitamin B6 are hypervitaminosis B6, as toxic levels may cause sensory neuropathy and hypersensitivity to pyridoxine. Vitamin B6 can be toxic if its concentration in the body is too high, causing sensory neuropathy, whose mechanism is unknown. Research on the subject found that the duration of administration of the vitamin is directly proportional to the risk of clinically evident toxicity with respect to the total dose given.
COVID-19 Impact on Vitamin B6 (Pyridoxine) Market
COVID-19 has affected the healthcare industry. To curb its growth, government-imposed lockdown. People are fearful they will experience occupational effects and adverse health from the COVID-19 pandemic. This affects the vitamin B6 (Pyridoxine) market as many pharmaceutical industries have stopped manufacturing units.
Vitamin B6 (Pyridoxine) Market Segment Analysis
Tablet’s segment will dominate the vitamin B6 (Pyridoxine) Market
Tablets are solid dosage forms consisting of the active ingredient and suitable pharmaceutical excipients. They are easy to carry, easy to swallow. They are attractive and easy to self-administration. Tablet does not require any measurement of dose.
In people with insufficient vitamins in their diets, pyridoxine (vitamin B6) is used to prevent or treat low levels of vitamin B6. Most of them who eat a normal diet do not need extra vitamin B6. However, some conditions (such as liver disease, overactive thyroid,alcoholism, heart failure) or medications (such as cycloserine, hydralazine, isoniazid, penicillamine) can cause low levels of vitamin B6. Vitamin B6 plays an important role in the body. It is needed to maintain the health of nerves, skin, and red blood cells. Pyridoxine has been used to prevent or treat a certain nerve disorder (peripheral neuropathy) caused by certain medications (such as isoniazid). It has also been used to treat certain hereditary disorders (xanthurenic aciduria, hyperoxaluria, homocystinuria). Pyridoxine is available under the following different brand names vitamin B6 and Nestrex.
The menopausal depression segment will dominate the vitamin B6 (Pyridoxine) market in the forecast period
Vitamin B-6 (pyridoxine) helps in making a chemical responsible for transmitting brain signals known as serotonin. Serotonin levels drop as women age such fluctuating serotonin levels may be a contributing factor in the depression and mood swings common in menopause. The hormonal havoc of menopause added to other common midlife changes, such as a decline in energy production and decreased body ability to absorb nutrients, can make menopause more challenging. The first step to regain physical and emotional balance is to take a diet which is rich in foods with high vitamin B6 and will also provide other important nutrients.
The RDA of vitamin B-6 is 100 milligrams (mg) daily for females 19 and older. Taking a vitamin B-6 supplement during and after menopause may help prevent symptoms caused by low serotonin levels. These include loss of energy and depression. Research shows that taking 50–80 mg of B6 supplements daily may help with symptoms of premenstrual syndrome (PMS), such as moodiness, irritability, anxiety and depression.
Vitamin B6 (Pyridoxine) Market Geographical Share
North America region will dominate the vitamin B6 (Pyridoxine) market
With increased research and development activity, the deficiency of vitamin B6, and major key players' presence, this region will dominate the Vitamin B6 (Pyridoxine) Market
According to U.S. Food and Drug Administration (FDA), About 28 percent to 36 percent of the normal population uses food supplements that contain vitamin B6 (pyridoxine). According to the National Institutes of Health (NIH), vitamin B6 deficiency is rare in the United States, but it can cause anemia, similar to iron deficiency anemia. In the US National Health and Nutrition Examination Survey (NHANES), over 40% of young adult women (21–44 years) had B6 deficiency (defined as having plasma PLP concentration < 20 nmol/L.
Vitamin B6 (Pyridoxine) Market Competitive Landscape
Teva pharmaceutical, Royal DSM N.V., Jiangxi Tianxin Pharmaceutical Co. Ltd., BASF SE, Huazhong Pharmaceutical, Acebright Pharmaceuticals Group, Now Foods, Shanghai Hegno Pharmaceutical Holding Co., Ltd., and Nanjing Pharmaceutical Factory Co. Ltd.
Vitamin B6 (Pyridoxine) Market Key Companies to Watch
Teva pharmaceuticals
Overview: For more than a century Teva Pharmaceuticals has been developing and producing medicines to help improve people’s lives. They are global leaders commited in generic and specialty medicines with a portfolio of 3,500 products in nearly every therapeutic area. Every day approximately 200 million people around the world take Teva medicine. They are served by one of the most complex and largest supply chains in the pharmaceutical industry.
Product Portfolio: The company is engaged in manufacturing generic medicines, specialty medicines, CNS, active pharmaceutical ingredients, respiratory, biosimilars, biologics, pain care, migraine, and oncology.
Key Development: Teva has released pyridoxine hydrochloride and doxylamine succinate delayed-release tablets in strength of 10 mg respectively. The drug, a generic version of Duchesnay's Diclegis is used to treat vomiting and nausea associated with pregnancy in women who have not improved with a diet change or other nonmedical treatments. The drug is available in bottles of 100 tablets.
The vitamin B6 (Pyridoxine) market report would provide an access to an approx. 53 market data table, 45 figures and 200 pages.
