Market Overview
The Global Bone Grafts and Substitutes Market reached US$ 3.46 billion in 2023 and is expected to reach US$ 5.77 billion by 2031, growing at a CAGR of 6.6% during the forecast period 2024-2031.
Bone grafts and substitutes are used for repairing bone defects or bone-related disorders. Different types of bone grafts are preferred such as allografts, synthetic bone grafts, or substitutes. The osteoconductive matrix acts as a filler to facilitate healing. Apart from these, the ceramics and polymer-based materials are bioresorbable and thermally non-conductive which doesn't lead to inflammatory reactions.
Market Summary
| Metrics | Details |
| CAGR | 6.6% |
| Market Size Available for Years | 2023-2031 |
| Estimation Forecast Period | 2024-2031 |
| Revenue Units | Value (US$ Mn) |
| Segments Covered | Product Type, Material, Application, End User |
| Regions Covered | North America, Europe, Asia-Pacific, South America, and Middle East & Africa |
| Largest Region | North America |
| Fastest Growing Region | Asia-Pacific |
| Report Insights Covered | Competitive Landscape Analysis, Company Profile Analysis, Market Size, Share, Growth, Demand, Recent Developments, Mergers and Acquisitions, New Product Launches, Growth Strategies, Revenue Analysis, Porter’s Analysis, Pricing Analysis, Regulatory Analysis, Supply-Chain Analysis, and Other key Insights. |
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Market Dynamics
Rising Incidence of Bone and Joint Disorders
The increasing incidence of osteoarthritis is expected to drive the market in the forthcoming period. Osteoarthritis is a degenerative joint disorder that is more prevalent in the older population. The increasing geriatric population also adds to the rising prevalence in different regions.
For instance, according to the World Health Organization, 2023, about 73% of people living with osteoarthritis are older than 55 years, and 60% are female. More than 344 million people living with osteoarthritis experience severity levels (moderate or severe) that could benefit from rehabilitation.
Furthermore, according to the Institute of Health Metrics and Evaluation, cases of other musculoskeletal disorders are projected to increase by 115% from 2020 to 2050, to an estimated 1060 million prevalent cases in 2050.
High cost of bone grafts
The high cost of bone grafts and substitutes especially dental bone grafting hinders the market because middle and low-income families may not be able to afford dental bone grafts due to the exceeding cost of grafts. For instance, the cost of dental bone grafting varies depending on several factors. On average, the cost ranges from $3,000 to $8,000 per graft in Australia. However, it can be as high as $5,000 or more for complex cases. It can be £500 and £3,000 in the UK, depending on the complexity of the procedure and the materials used.
Market Segmentation Analysis
The global bone grafts and substitutes market is segmented based on product type, material, application, end-user and region.
Bone graft substitutes product type is expected to dominate the market
Bone graft substitutes are expected to hold the largest share of the market due to increasing product launches in the market. Synthetic bone grafts act as replicas for the normal bones. These are made up of synthetic such as polymer-based or ceramic materials. For instance, in February 2022, Orthofix Medical Inc. launched a new synthetic bioactive bone graft solution called Opus B.A., used for cervical and lumbar spine fusion procedures.
In October 2023, Orthofic Medical Inc. launched its OsteoCoveTM, a bioactive synthetic graft. The graft is designed for exceptional bone reforming properties in both a putty and strip version.
Furthermore, in January 2023, Nobel Biocare introduced creosTM syntogain, a biomimetic bone graft alternative in collaboration with Mimetis Biomaterials S.L. The collaboration offers unique solutions to enhance patient care.
Market Geographical Share
North America is expected to dominate the global market
The increasing geriatric population in the US and other North America regions is expected to hold the largest share of the market. For instance, according to the Pew Research Center, 2023, There are currently roughly 62 million adults ages 65 and older living in the U.S., accounting for 18% of the population.
By 2054, 84 million adults ages 65 and older will make up an estimated 23% of the population. Furthermore, according to the Population Reference Bureau, 2024, the number of Americans ages 65 and older is projected to increase from 58 million in 2022 to 82 million by 2050
Key Developments
- In May 2023, Locate Bio, received the US Food and Drug Administration clearance for its breakthrough device designation for LD Graft.
- In April 2023, ZimVie Inc. introduced two new biomaterials to its product portfolio. RegenerOss Bone Graft Plug, an easy-to-use grafting solution for periodontal defects and extraction sockets, and RegenerOss CC Allograft Particulate, a natural blend of cortical and cancellous bone particles that can be used to fill bony voids in a variety of dental applications.
Market Key Players
The major global players in the market include Orthofix Medical Inc., DePuy Synthes, Integra LifeSciences, NuVasive, Inc., Stryker Corporation, Wright Medical Group N.V., Xtant Medical, Zimmer Biomet, Baxter International Inc., Medtronic Plc. among others.
Why Purchase the Report?
- To visualize the bone grafts and substitutes market segmentation based on product type, material, application, end user, and region as well as understand key commercial assets and players.
- Identify commercial opportunities by analyzing trends and co-development.
- Excel data sheet with numerous data points of bone grafts and substitutes market-level with all segments.
- PDF report consists of a comprehensive analysis after exhaustive qualitative interviews and an in-depth study.
- Product mapping available as excel consisting of key products of all the major players.
The global bone grafts and substitutes market report would provide approximately 64 tables, 70 figures and 186 pages.
Target Audience 2024
- Manufacturers/ Buyers
- Industry Investors/Investment Bankers
- Research Professionals
- Emerging Companies
