Global Anal Cancer Market is segmented By Cancer Type (Squamous cell carcinoma, Adenocarcinoma, Basal cell carcinoma, Melanoma, Others), By Treatment Type (Chemotherapy, Immunotherapy, Surgery, Radiation therapy, Others), By End-users (Hospitals, Clinics, Cancer research institutes, Others), and By Region (North America, South America, Europe, Asia Pacific, Middle East, and Africa) – Share, Size, Outlook, and Opportunity Analysis, 2023-2030
Anal Cancer Market Overview
The Global Anal Cancer Market report analyzes the market shares, size, recent trends, future market outlook, and competitive intelligence. Anal cancer is a rare form of cancer that develops in the tissues of the anus. The market is driven by the increasing incidence globally of anal cancer, growing awareness regarding the diagnosis and treatment of anal cancer, and the development of novel therapies for the treatment of anal cancer. Key players in the Global Anal Cancer Market include Merck & Co., Inc., Bristol-Myers Squibb Company, F. Hoffmann-La Roche Ltd, Pfizer Inc., and other prominent players operating in the market.
Anal cancer is a rare type of cancer in the anal canal, which is a short tube at the end of your rectum through which stool leaves your body. Anal cancer is often called squamous cell carcinoma, which arises from the cells around or in the anal opening or, in rare cases, it may cause in the anal canal. This type of cancer is usually associated with human papillomavirus (HPV), where HPV cancers or cervical cancers have a high risk of developing into anal cancer. There are no exact symptoms for anal cancer, but some might show bleeding from the anal area, lump or swelling near the anus, or change in bowel habits.
Staging is a way that describes the location of cancer; the stages include tumor, node, and metastasis, which are further grouped into I, II, IIIA, IIIB, and IV. The different types of anal cancer include melanoma, adenocarcinoma, basal cell carcinoma, and gastrointestinal stromal tumor (GIST) and most people with anal cancer are treated with a combination of chemotherapy and radiation, called chemoradiation. Combining treatments increases the chance of a cure.
Anal Cancer Market Summary
| Metrics | Details |
| Market CAGR | High |
| Segments Covered | By Cancer Type, By Treatment Type, By End-users, and By Region |
| Report Insights Covered | Competitive Landscape Analysis, Company Profile Analysis, Market Size, Share, Growth, Demand, Recent Developments, Mergers and acquisitions, New Product Launches, Growth Strategies, Revenue Analysis, and Other key insights. |
| Fastest Growing Region | Asia Pacific |
| Largest Market Share | North America |
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Anal Cancer Market Dynamics and Trends
The global Anal cancer growth is driven by the increasing prevalence of Anal cancers worldwide, changing lifestyles and increasing smoking habits, Rising investment in research and development activities, and Growing initiatives by the government to spread awareness about anal cancers among the public are the major factors driving the market.
The increasing prevalence of Anal cancers worldwide is expected to drive growth in the forecast period
The American Cancer Society stated about 8,300 cases of anal cancer in 2019. Females account for about 5,530 of these cases. The number of cases of anal cancer has been on the rise in the past several years. In the United States, in 2021, there will be about 9,090 new cases (6,070 in women and 3,020 in men). Anal cancer is rare in younger people of less than 35 and is found mainly in older adults, with an average age being in the early 60s. It is also more common in white women and black men.
High treatment costs are likely to hinder market growth.
According to the American cancer clinical society, approximate Anal Cancer Treatment cost in India is the range between USD 1500 to USD 15,000 which is a burden for underdeveloped and developing countries. This is one of the major factors restricting market growth.
COVID-19 Impact on Anal Cancer Market Growth
The COVID-19 pandemic has negatively impacted healthcare systems globally and on the vulvar Cancer market. The Centers for Disease Control and Prevention (CDC) and many medical professional organizations recommended that cancer screening and other health prevention services, along with elective surgeries, be postponed unless the risks outweighed the benefits and secure the hospital infrastructure for the treatment of COVID-19 patients. Thus, the COVID-19 pandemic has impacted the Ongoing clinical trials too. However, the situation is expected to improve gradually.
Anal Cancer Market Segment Analysis
Based on the Cancer Type, the global Anal Cancer market is segmented into Squamous cell carcinoma, Melanoma, and Adenocarcinoma, zr the largest share in the cancer type segment
Squamous cell carcinoma in the anal canal has grown beyond the surface and into the deeper layers of the lining. Nearly 9 out of 10 cases of anal cancers in the United States are squamous cell cancer. These tumors start in the squamous cells that line most of the anal canal and the anal margin.
2 out of 10 small anal cancers are adenocarcinomas. These cancers start in cells that line the upper part of the anus near the rectum. They can also start in the glands under the anal mucosa that release secretions into the anal canal.
Based on the Treatment Type, the global Anal Cancer market is segmented into Chemotherapy, Surgery, Radiation therapy and Immunotherapy and Others
The chemotherapy and Immunotherapy segment is expected to hold the largest in the market.
Chemotherapy treatment uses anti-cancer drugs that can be swallowed in pill form or injected into a vein. The drugs travel through the bloodstream to reach most parts of the body. In most cases, two or more drugs are used at the same time to shrink cancer. The main drug combination used to treat anal cancer is 5-fluorouracil (5-FU) and mitomycin. The combination of 5-FU and cisplatin can also be used, especially in people who can't get mitomycin or advanced anal cancer. In particular, people who may be older or can't tolerate two chemotherapy drugs, 5-FU alone, may be given radiation. For advanced anal cancer or anal cancer that has already been treated with 5-FU and mitomycin, other options for chemotherapy include Carboplatin with paclitaxel (Taxol), 5-FU with cisplatin, Oxaliplatin, Leucovorin and 5-FU, Docetaxel (Taxotere), cisplatin and 5-FU, Cisplatin, Leucovorin, and 5-FU.
Immunotherapy treatment uses medicines to stimulate a person’s immune system to recognize and destroy cancer cells more effectively. Drugs like nivolumab (Opdivo) and pembrolizumab (Keytruda) target PD-1, a protein on specific immune cells (called T cells) that usually helps to keep these cells from attacking the other cells in the body, by blocking PD-1, these drugs boost the immune response against cancer cells and shrink some tumors or slow their growth. These drugs can also be used in people with metastasized anal cancer and whose cancer starts growing after getting at least one type of chemotherapy.
For instance, In July 2019, Merck & Co., Inc developed Keytruda (pembrolizumab), a monoclonal antibody that binds to the PD-1 receptor. This drug is approved for multiple oncology indications and is now ongoing in a phase II clinical trial for the treatment of anal cancer.
Based on End-User, the global Anal Cancer market is segmented into Hospitals, Cancer Research centers, clinics, and others.
Due to the growing patient population, the hospital's segment held the largest market share. This is mainly owing to the increasing number of patients suffering from conditions that are treated in hospitals equipped with advanced infrastructure and adequate facilities. Moreover, the growing number of hospitals along with adequate reimbursement policies is also contributing to the growth of this segment. Also, the medications can only be administrated intravenously and surgery is done under the supervision of medical practitioners at these locations.
Anal Cancer Market Geographical Share
North America holds the largest market in the global anal cancer market due to the high incidence of cancer, according to the International Agency for Research on Cancer (IARC), which claims 13 million new cancer cases worldwide. The World Cancer Report provides that the incidence rate of new cancer cases increased by 50% to 15 million in 2020. The existence of a highly developed healthcare system, the high degree of acceptance by medical practitioners of novel chemotherapy and radiation therapy methods, the total availability of advanced technological tools, FDA approval of new drugs, and also the presence of a vast number of organizations engaged in R&D activities related to cancer vaccines.
The Asia Pacific is expected to be the fastest-growing market over the forecast period owing to the increasing prevalence rate, increasing focus on preventive care, and government initiatives promoting technological innovations. For instance, A Phase III Trial of Chemoradiotherapy with or without Paclitaxel in Patients with Squamous-cell Anal Cancer conducted by Blokhin's Russian Cancer Research Center is expected to complete by 2022.
Anal Cancer Market Companies and Competitive Landscape
The Global Anal Cancer Market is quite competitive with some key competitors like Advaxis, Inc, Inovio Pharmaceuticals, Inc, F. Hoffmann-La Roche Ltd, Merck & Co., Inc, Amgen Inc, Antiva Biosciences, Inc, Medtronic, Onconova Therapeutics, BioMimetix, Castle Biosciences, Inc among others. The major players are adopting several growth strategies such as product launches, acquisitions, and collaborations, contributing to the market’s growth globally. For instance, Advaxis, Inc completed Phase 2 clinical trials of ADXS11-001 in Subjects With Persistent/Recurrent, Loco-Regional, or Metastatic Squamous Cell Carcinoma of the Anorectal Canal.
Hoffmann-La Roche Ltd
Company Overview: Roche was founded in 1896 in Basel, Switzerland. It creates innovative medicines and diagnostic tests that help millions of patients globally. Roche was one of the first companies to bring targeted treatments to patients. With our combined strength in pharmaceuticals and diagnostics, we are better equipped than any other company to drive personalized healthcare further. Two-thirds of our Research and Development projects are being developed with companion diagnostics. Genentech become a member of the Roche Group in March of 2009.
Product Portfolio: The company portfolio includes Oncology, Neurology, Endocrinology, Infectious diseases, and others.
Key developments:
Roche Pharma AG is conducting a Phase II Study of Docetaxel, Cisplatin, and 5-fluorouracil in Combination or Not with atezolizumab in Patients with Metastatic or Unresectable Locally Advanced Squamous Cell Anal Carcinoma is expected to complete by 2022.
Why Purchase the Report?
- Visualize the composition of the Anal Cancer Market segmentation by Cancer type, Treatment type, End-users, and region highlighting the key commercial assets and players.
- Identify commercial opportunities in Anal Cancer Market by analyzing trends and co-development deals.
- Excel data sheet with thousands of data points of Anal Cancer Market - level 4/5 segmentation.
- PDF report with the most relevant analysis cogently put together after exhaustive qualitative interviews and in-depth market study.
- Product mapping in Excel for the key product of all major market players
The global Anal Cancer Market report would provide access to approx. 61 market data tables, 57 figures, and 180 pages.
Target Audience
- Service Providers/ Buyers
- Industry Investors/Investment Bankers
- Education & Research Institutes
- Research Professionals
- Emerging Companies
- Manufacturers
