Global Activin A Market is segmented By Application (Commercial Research, Academic Research), By Type (Activin A Human, Activin-A Mouse/Rat), and By Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) – Share, Size, Outlook, and Opportunity Analysis, 2024-2031
Activin A Market Overview
The "Global Activin A Market" is predicted to reach at a high CAGR of 3.8% during the forecast period (2024-2031)
Activin A is an important member of the TGF-beta superfamily that is produced by many different cell types and is essential for proper development. Bioactive Activin A exists as a disulfide-linked homodimer that recognizes and binds to four Activin receptors, Activin RIA and RIB, and Activin RIIA and RIIB.
Activin A Market Scope
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Metrics |
Details |
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Market CAGR |
3.8% |
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Segments Covered |
By Application, By Type, and By Region |
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Report Insights Covered |
Competitive Landscape Analysis, Company Profile Analysis, Market Size, Share, Growth, Demand, Recent Developments, Mergers and acquisitions, New Product Launches, Growth Strategies, Revenue Analysis, and Other key insights. |
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Fastest Growing Region |
Asia Pacific |
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Largest Market Share |
North America |
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Source: DataM Intelligence Analysis (2020)
Activin A Market Dynamics
The activin A market growth is driven by the rising prevalence of chronic diseases, growing company initiatives, and rising adoption of activin A owing to the benefits it offers.
Increasing usage of activin A owing to the benefits it offers, is expected to drive the growth in the forecast period
The most important functions of activin A are the regulation of cell differentiation. According to the National Center for Biotechnology Information, U.S. National Library of Medicine, Activin A controls several aspects of hematopoiesis and regulates cell differentiation in the ovary, placenta, prostate, and testis. During embryogenesis, it is instrumental for axis development and organogenesis in a variety of species. In adults, activins function as hormone-like feedback regulators in the reproductive system. Furthermore, the presence of activin has been related to wound healing. In the eye, members of the activin family have been discovered in retinal pigment epithelium. Activin A and its receptors were recently described in preretinal membranes from eyes with ischemic and nonischemic vitreoretinal proliferative diseases, a result that agrees with a role of activin A in neovascularization.
High cost of culture media will hamper the market growth
However, the high expensive culture media will be a significant market impeding factor. Activin A was expressed in E. coli using the pET 21a expression vector. For enhanced expression, the optimum IPTG and lactose concentrations were 1.5 mM and 0% W/V respectively. In the DE3 strain, the optimum post-induction time and temperature were 10 hours and 30°C respectively while in DE3 (plysS) these were 4 hours and 35°C respectively.
COVID-19 Impact Analysis
Since the COVID-19 virus outbreak in December 2019, the disease has spread to almost 100 countries around the globe with the World Health Organization declaring it a public health emergency. The global impacts of the coronavirus disease 2019 (COVID-19) are already starting to be felt, and will significantly affect the Activin-A market in 2021. COVID-19 can affect the global economy in three main ways: by directly affecting production and demand, by creating supply chain and market disruption, and by its financial impact on firms and financial markets.
Activin A Market Segment Analysis
The activin A human segment is expected to hold largest share in this market segment
Activin A human has been used as a constituent of modified barth′s saline used in in vitro induction of pronephros. It has also been used as a constituent of Roswell Park memorial institute (RPMI) media to induce pancreatic differentiation of multipotent dermal fibroblasts in vitro. In Cancer (such as breast cancer)- used in conjunction with other medications such as tamoxifen or hormone therapy to treat the metastatic disease which has spread from its original site. Activin A binds to certain receptors on cell membranes called "activin" receptors that sit near growth factor receptors like estrogen receptor alpha or progesterone receptor. When activin A binds to cells containing these signaling surface molecules, it can stimulate nearby DNA synthesis without requiring mitogens like epidermal growth factor (EGF).
The commercial research segment is expected to hold largest share in this market segment
Commercial research accounts largest share due to presence of wide applications in many therapeutic areas such as epithelial cell biology, stem cell biology etc.
Source: DataM Intelligence Analysis (2020)
Activin A Market Geographical Share
North America region holds the largest market share of global activin A market
North America region accounted for the largest share of the Activin A market owing to various factors such as increasing cases of asthma that require administration of Activin-A injections. Asthma affected an estimated 262 million people in 2019 and caused 461000 deaths. According to the National Current Asthma Prevalence (2019) around 25,131,132 7.8 (0.17) Children (Age <18 years) 5,104,410 7.0 (0.34) Adults (Age 18+ years) 20,026,722 8.0.
Activin A Market Companies and Competitive Landscape
The global activin A market is highly competitive with presence of global companies. Some of the key players which are contributing to the growth of the market include Merck Millipore, Thermo Fisher Scientific, Bio-Techne, StemRD, Prospec, Proteintech Group (china), Ajinomoto, Enzo Life Sciences, IBL, STEMCELL, Sino Biological, Beijing Sizhengbai Biotechnology Co., Ltd, Shanghai yiji industries Co., Ltd. The major players are adopting several growth strategies such as product launches, acquisitions, and collaborations, which are contributing to the growth of the market globally.
Activin A Market Key Companies to Watch
Merck Millipore
Overview: Merck Millipore was the brand used by Merck Group's global life science business until 2015 when the company re-branded. It was formed when Merck acquired the Millipore Corporation in 2010. Merck is a supplier to the life science industry. The Millipore Corporation was founded in 1954, and listed among the S&P 500 since the early 1990s, as an international biosciences company which makes micrometer pore-size filters and tests. In 2015, Merck acquired Sigma-Aldrich and merged it with Merck Millipore. In the United States and Canada, the life science business is now known as MilliporeSigma.
Product Portfolio: The Company’s portfolio comprised of include analytics and sample preparation, biopharmaceutical manufacturing, industrial Microbiology, life science research, reagents, chemicals and labware.
Product: 114700 Sigma-Aldrich Activin A, Human, Recombinant, CHO Cells.
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- Visualize the composition of the activin A market segmentation by type, application and region highlighting the key commercial assets and players.
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The global activin A market report would provide an access to an approx. 53 market data table, 40 figures and 200 pages.
Target Audience
- Service Providers/ Buyers
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- Education & Research Institutes
- Research Professionals
- Emerging Companies
- Manufacturers
